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Crystal Structure of the Virulence Gene Activator AphA from Vibrio cholerae Reveals It Is a Novel Member of the Winged Helix Transcription Factor Superfamily

AphA is a member of a new and largely uncharacterized family of transcriptional activators that is required for initiating virulence gene expression in Vibrio cholerae, the causative agent of the frequently fatal epidemic diarrheal disease cholera. AphA activates transcription by an unusual mechanis...

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Bibliographische Detailangaben
Hauptverfasser: De Silva, Rukman S., Kovacikova, Gabriela, Lin, Wei, Taylor, Ronald K., Skorupski, Karen, Kull, F. Jon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652724/
https://ncbi.nlm.nih.gov/pubmed/15647287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M413781200
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