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Crystal Structure of the Virulence Gene Activator AphA from Vibrio cholerae Reveals It Is a Novel Member of the Winged Helix Transcription Factor Superfamily

AphA is a member of a new and largely uncharacterized family of transcriptional activators that is required for initiating virulence gene expression in Vibrio cholerae, the causative agent of the frequently fatal epidemic diarrheal disease cholera. AphA activates transcription by an unusual mechanis...

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Detalhes bibliográficos
Main Authors: De Silva, Rukman S., Kovacikova, Gabriela, Lin, Wei, Taylor, Ronald K., Skorupski, Karen, Kull, F. Jon
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652724/
https://ncbi.nlm.nih.gov/pubmed/15647287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M413781200
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