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The Fatty Acid Regulator FadR Influences the Expression of the Virulence Cascade in the El Tor Biotype of Vibrio cholerae by Modulating the Levels of ToxT via Two Different Mechanisms

FadR is a master regulator of fatty acid (FA) metabolism that coordinates the pathways of FA degradation and biosynthesis in enteric bacteria. We show here that a ΔfadR mutation in the El Tor biotype of Vibrio cholerae prevents the expression of the virulence cascade by influencing both the transcri...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Main Authors: Kovacikova, Gabriela, Lin, Wei, Taylor, Ronald K., Skorupski, Karen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350278/
https://ncbi.nlm.nih.gov/pubmed/28115548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00762-16
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