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Modified ToxT inhibitor reduces Vibrio cholerae virulence in vivo
We have previously designed and synthesized small-molecule inhibitors that reduce Vibrio cholerae virulence in vitro by targeting the transcription factor ToxT. Here we report the synthesis and biological activity of derivatives of our previous bicyclic, fatty acid-like inhibitors. All of the synthe...
Gardado en:
| Publicado en: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528795/ https://ncbi.nlm.nih.gov/pubmed/30160100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00667 |
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