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Modified ToxT inhibitor reduces Vibrio cholerae virulence in vivo
We have previously designed and synthesized small-molecule inhibitors that reduce Vibrio cholerae virulence in vitro by targeting the transcription factor ToxT. Here we report the synthesis and biological activity of derivatives of our previous bicyclic, fatty acid-like inhibitors. All of the synthe...
में बचाया:
| में प्रकाशित: | Biochemistry |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528795/ https://ncbi.nlm.nih.gov/pubmed/30160100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00667 |
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