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Modified ToxT inhibitor reduces Vibrio cholerae virulence in vivo
We have previously designed and synthesized small-molecule inhibitors that reduce Vibrio cholerae virulence in vitro by targeting the transcription factor ToxT. Here we report the synthesis and biological activity of derivatives of our previous bicyclic, fatty acid-like inhibitors. All of the synthe...
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| Publicat a: | Biochemistry |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6528795/ https://ncbi.nlm.nih.gov/pubmed/30160100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00667 |
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