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Structure-Function Relationships in Lactate Dehydrogenase

The binding of coenzyme and substrate are considered in relation to the known primary and tertiary structure of lactate dehydrogenase (EC 1.1.1.27). The adenine binds in a hydrophobic crevice, and the two coenzyme phosphates are oriented by interactions with the protein. The positively charged guani...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Adams, Margaret J., Buehner, Manfred, Chandrasekhar, K., Ford, Geoffrey C., Hackert, Marvin L., Liljas, Anders, Rossmann, Michael G., Smiley, Ira E., Allison, William S., Everse, Johannes, Kaplan, Nathan O., Taylor, Susan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1973
Assuntos:
Biological Sciences: Biochemistry
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4146647/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.7.1968
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