Structure-Function Relationships in Lactate Dehydrogenase

The binding of coenzyme and substrate are considered in relation to the known primary and tertiary structure of lactate dehydrogenase (EC 1.1.1.27). The adenine binds in a hydrophobic crevice, and the two coenzyme phosphates are oriented by interactions with the protein. The positively charged guani...

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Bibliografische gegevens
Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Adams, Margaret J., Buehner, Manfred, Chandrasekhar, K., Ford, Geoffrey C., Hackert, Marvin L., Liljas, Anders, Rossmann, Michael G., Smiley, Ira E., Allison, William S., Everse, Johannes, Kaplan, Nathan O., Taylor, Susan S.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1973
Onderwerpen:	Biological Sciences: Biochemistry
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433644/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4146647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.7.1968
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Structure-Function Relationships in Lactate Dehydrogenase

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