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Structure-Function Relationships in Lactate Dehydrogenase

The binding of coenzyme and substrate are considered in relation to the known primary and tertiary structure of lactate dehydrogenase (EC 1.1.1.27). The adenine binds in a hydrophobic crevice, and the two coenzyme phosphates are oriented by interactions with the protein. The positively charged guani...

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Bibliografiske detaljer
Main Authors: Adams, Margaret J., Buehner, Manfred, Chandrasekhar, K., Ford, Geoffrey C., Hackert, Marvin L., Liljas, Anders, Rossmann, Michael G., Smiley, Ira E., Allison, William S., Everse, Johannes, Kaplan, Nathan O., Taylor, Susan S.
Format: Artigo
Sprog:Inglês
Udgivet: 1973
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC433644/
https://ncbi.nlm.nih.gov/pubmed/4146647
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