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FabH Mutations Confer Resistance to FabF-Directed Antibiotics in Staphylococcus aureus

Delineating the mechanisms for genetically acquired antibiotic resistance is a robust approach to target validation and anticipates the evolution of clinical drug resistance. This study defines a spectrum of mutations in fabH that render Staphylococcus aureus resistant to multiple natural products k...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Parsons, Joshua B., Yao, Jiangwei, Frank, Matthew W., Rock, Charles O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335864/
https://ncbi.nlm.nih.gov/pubmed/25403676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04179-14
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