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Discovery of FabH/FabF Inhibitors from Natural Products

Condensing enzymes are essential in type II fatty acid synthesis and are promising targets for antibacterial drug discovery. Recently, a new approach using a xylose-inducible plasmid to express antisense RNA in Staphylococcus aureus has been described; however, the actual mechanism was not delineate...

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Bibliografski detalji
Glavni autori: Young, Katherine, Jayasuriya, Hiranthi, Ondeyka, John G., Herath, Kithsiri, Zhang, Chaowei, Kodali, Srinivas, Galgoci, Andrew, Painter, Ronald, Brown-Driver, Vickie, Yamamoto, Robert, Silver, Lynn L., Zheng, Yingcong, Ventura, Judith I., Sigmund, Janet, Ha, Sookhee, Basilio, Angela, Vicente, Francisca, Tormo, José Rubén, Pelaez, Fernando, Youngman, Phil, Cully, Doris, Barrett, John F., Schmatz, Dennis, Singh, Sheo B., Wang, Jun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366929/
https://ncbi.nlm.nih.gov/pubmed/16436705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.519-526.2006
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