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The phosphoinositide 3-kinase pathway and therapy resistance in cancer
The phosphoinositide 3-kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR) signaling network is a master regulator of processes that contribute to tumorigenesis and tumor maintenance. The PI3K pathway also plays a critical role in driving resistance to diverse anti-cancer therapies. This review...
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| Publicado no: | F1000Prime Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Faculty of 1000 Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4335789/ https://ncbi.nlm.nih.gov/pubmed/25750731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P7-13 |
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