Inhibition of the phosphoinositide 3-kinase pathway for the treatment of patients with metastatic metaplastic breast cancer

BACKGROUND: Mesenchymal/metaplastic breast cancers (MpBCs) are often triple-negative (TNBC), and chemo-refractory, and can harbor phosphoinositide 3-kinase (PI3kinase) alterations; thus, therapy with mTor inhibitors may demonstrate activity. PATIENTS AND METHODS: Patients with mesenchymal/MpBC treat...

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Bibliografiska uppgifter
I publikationen:Ann Oncol
Huvudupphovsmän: Moulder, S., Helgason, T., Janku, F., Wheler, J., Moroney, J., Booser, D., Albarracin, C., Morrow, P. K., Atkins, J., Koenig, K., Gilcrease, M., Kurzrock, R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6267938/
https://ncbi.nlm.nih.gov/pubmed/25878190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdv163
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