Comparative Effectiveness of an mTOR‐Based Systemic Therapy Regimen in Advanced, Metaplastic and Nonmetaplastic Triple‐Negative Breast Cancer

BACKGROUND. Triple‐negative breast cancer (TNBC) is a heterogeneous disease with subtypes having different “targetable” molecular aberrations. Metaplastic breast cancers (MpBCs) are typically TNBCs and commonly have alterations in the PI3K/Akt/mTOR pathway. We previously reported efficacy for an mTO...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Basho, Reva K., Yam, Clinton, Gilcrease, Michael, Murthy, Rashmi K., Helgason, Thorunn, Karp, Daniel D., Meric‐Bernstam, Funda, Hess, Kenneth R., Valero, Vicente, Albarracin, Constance, Litton, Jennifer K., Chavez‐MacGregor, Mariana, Hong, David, Kurzrock, Razelle, Hortobagyi, Gabriel N., Janku, Filip, Moulder, Stacy L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Breast Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291334/
https://ncbi.nlm.nih.gov/pubmed/30139837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0498
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