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Synthesis of novel spin-labeled podophyllotoxin derivatives as potential antineoplastic agents: Part XXV

A series of novel spin-labeled 4β-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin derivatives (17a–h) were firstly designed and synthesized with significant regioselectivity by employing Cu(I) catalyzed click approach, and evaluated for cytotoxicity against four human tumor cell lines (A-549, DU...

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Bibliografiske detaljer
Udgivet i:Med Chem Res
Main Authors: Yang, Liu, Nan, Xiang, Li, Wen-Qun, Wang, Mei-Juan, Zhao, Xiao-Bo, Liu, Ying-Qian, Zhang, Zhi-Jun, Lee, Kuo-Hsiung
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335759/
https://ncbi.nlm.nih.gov/pubmed/25709376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-014-1042-9
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