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Synthesis of novel spin-labeled derivatives of 5-FU as potential antineoplastic agents

Chemotherapy is a general treatment option for various cancers, including lung cancer. In order to find compounds with superior bioactivity and less toxicity against lung cancer, novel spin-labeled 5-fluorouracil (5-FU) derivatives (3a–f) were synthesized and evaluated against four human tumor cell...

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Détails bibliographiques
Publié dans:Med Chem Res
Auteurs principaux: Yang, Liu, Wang, Mei-Juan, Zhang, Zhi-Jun, Morris-Natschke, Susan L., Goto, Masuo, Tian, Jing, Liu, Ying-Qian, Wang, Chih-Ya, Tian, Xuan, Yang, Xiao-Ming, Lee, Kuo-Hsiung
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337784/
https://ncbi.nlm.nih.gov/pubmed/25722628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-013-0906-8
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