A high-sensitivity phospho-switch triggered by Cdk1 governs chromosome morphogenesis during cell division

The initiation of chromosome morphogenesis marks the beginning of mitosis in all eukaryotic cells. Although many effectors of chromatin compaction have been reported, the nature and design of the essential trigger for global chromosome assembly remain unknown. Here we reveal the identity of the core...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Robellet, Xavier, Thattikota, Yogitha, Wang, Fang, Wee, Tse-Luen, Pascariu, Mirela, Shankar, Sahana, Bonneil, Éric, Brown, Claire M., D’Amours, Damien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335297/
https://ncbi.nlm.nih.gov/pubmed/25691469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.253294.114
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