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Cdk1-dependent regulation of the Mre11 complex couples DNA repair pathways to cell cycle progression
Homologous recombination (HR) and non-homologous end joining (NHEJ) are the main pathways ensuring the repair of DNA double-stranded breaks (DSBs) in eukaryotes. It has long been known that cell cycle stage is a major determinant of the type of pathway used to repair DSBs in vivo. However, the mecha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013159/ https://ncbi.nlm.nih.gov/pubmed/24553123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27946 |
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