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Cdk1-dependent regulation of the Mre11 complex couples DNA repair pathways to cell cycle progression

Homologous recombination (HR) and non-homologous end joining (NHEJ) are the main pathways ensuring the repair of DNA double-stranded breaks (DSBs) in eukaryotes. It has long been known that cell cycle stage is a major determinant of the type of pathway used to repair DSBs in vivo. However, the mecha...

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Sonraí Bibleagrafaíochta
Main Authors: Simoneau, Antoine, Robellet, Xavier, Ladouceur, Anne-Marie, D’Amours, Damien
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013159/
https://ncbi.nlm.nih.gov/pubmed/24553123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27946
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