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A high-sensitivity phospho-switch triggered by Cdk1 governs chromosome morphogenesis during cell division

The initiation of chromosome morphogenesis marks the beginning of mitosis in all eukaryotic cells. Although many effectors of chromatin compaction have been reported, the nature and design of the essential trigger for global chromosome assembly remain unknown. Here we reveal the identity of the core...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Robellet, Xavier, Thattikota, Yogitha, Wang, Fang, Wee, Tse-Luen, Pascariu, Mirela, Shankar, Sahana, Bonneil, Éric, Brown, Claire M., D’Amours, Damien
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335297/
https://ncbi.nlm.nih.gov/pubmed/25691469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.253294.114
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