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Toxicity of an α-Pore-forming Toxin Depends on the Assembly Mechanism on the Target Membrane as Revealed by Single Molecule Imaging

α-Pore-forming toxins (α-PFTs) are ubiquitous defense tools that kill cells by opening pores in the target cell membrane. Despite their relevance in host/pathogen interactions, very little is known about the pore stoichiometry and assembly pathway leading to membrane permeabilization. Equinatoxin II...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Subburaj, Yamunadevi, Ros, Uris, Hermann, Eduard, Tong, Rudi, García-Sáez, Ana J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335225/
https://ncbi.nlm.nih.gov/pubmed/25525270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600676
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