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Loss of dihydrolipoyl succinyltransferase (DLST) leads to reduced resting heart rate in the zebrafish

The genetic underpinnings of heart rate regulation are only poorly understood. In search for genetic regulators of cardiac pacemaker activity, we isolated in a large-scale mutagenesis screen the embryonic lethal, recessive zebrafish mutant schneckentempo (ste). Homozygous ste mutants exhibit a sever...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Basic Res Cardiol
Egile Nagusiak: Keßler, Mirjam, Berger, Ina M., Just, Steffen, Rottbauer, Wolfgang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335124/
https://ncbi.nlm.nih.gov/pubmed/25697682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-015-0468-7
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