Acetylation of Sickle Cell Hemoglobin by Aspirin
Incubation of HbS (or HbA) with aspirin leads to incorporation of acetyl groups into the protein. Incorporation was followed by the use of aspirin labeled with (14)C in the acetyl group. The acetylated hemoglobins show an increase in oxygen affinity compared to the parent proteins. If acetylation al...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1973
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433486/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4514302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.5.1313 |
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