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Acetylation of Sickle Cell Hemoglobin by Aspirin

Incubation of HbS (or HbA) with aspirin leads to incorporation of acetyl groups into the protein. Incorporation was followed by the use of aspirin labeled with (14)C in the acetyl group. The acetylated hemoglobins show an increase in oxygen affinity compared to the parent proteins. If acetylation al...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Klotz, Irving M., Tam, Joseph W. O.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1973
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433486/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4514302/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.5.1313
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