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Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activity

Extracellular signal-regulated kinase (ERK) plays a central role in signal transduction networks and cell fate decisions. Sustained ERK activation induces cell differentiation, whereas transient ERK results in the proliferation of several types of cells. Sustained ERK activity stabilizes the protein...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Nagashima, Takeshi, Inoue, Norihiko, Yumoto, Noriko, Saeki, Yuko, Magi, Shigeyuki, Volinsky, Natalia, Sorkin, Alexander, Kholodenko, Boris N, Okada-Hatakeyama, Mariko
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334673/
https://ncbi.nlm.nih.gov/pubmed/25491268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13172
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