Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells

BACKGROUND: Sharing a common ErbB/HER receptor signaling pathway, heregulin (HRG) induces differentiation of MCF-7 human breast cancer cells while epidermal growth factor (EGF) elicits proliferation. Although cell fates resulting from action of the aforementioned ligands completely different, the re...

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Bibliografiske detaljer
Main Authors: Saeki, Yuko, Endo, Takaho, Ide, Kaori, Nagashima, Takeshi, Yumoto, Noriko, Toyoda, Tetsuro, Suzuki, Harukazu, Hayashizaki, Yoshihide, Sakaki, Yoshiyuki, Okada-Hatakeyama, Mariko
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785842/
https://ncbi.nlm.nih.gov/pubmed/19925682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-10-545
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