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Signalling mechanisms regulating phenotypic changes in breast cancer cells

In MCF-7 breast cancer cells epidermal growth factor (EGF) induces cell proliferation, whereas heregulin (HRG)/neuregulin (NRG) induces irreversible phenotypic changes accompanied by lipid accumulation. Although these changes in breast cancer cells resemble processes that take place in the tissue, t...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Volinsky, Natalia, McCarthy, Cormac J., von Kriegsheim, Alex, Saban, Nina, Okada-Hatakeyama, Mariko, Kolch, Walter, Kholodenko, Boris N.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370098/
https://ncbi.nlm.nih.gov/pubmed/25643809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140172
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