Fractional exhaled nitric oxide in childhood is associated with 17q11.2-q12 and 17q12-q21 variants

BACKGROUND: The fractional concentration of nitric oxide in exhaled air (FeNO) is a biomarker of eosinophilic airway inflammation and associated with childhood asthma. Identification of common genetic variants associated with childhood FeNO may help to define biological mechanisms related to specifi...

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Publicado no:J Allergy Clin Immunol
Main Authors: van der Valk, Ralf JP, Duijts, Liesbeth, Timpson, Nicolas J, Salam, Muhammad T, Standl, Marie, Curtin, John A, Genuneit, Jon, Kerhof, Marjan, Kreiner-Møller, Eskil, Cáceres, Alejandro, Gref, Anna, Liang, Liming L, Taal, H Rob, Bouzigon, Emmanuelle, Demenais, Florence, Nadif, Rachel, Ober, Carole, Thompson, Emma E, Estrada, Karol, Hofman, Albert, Uitterlinden, André G, van Duijn, Cornélia, Rivadeneira, Fernando, Li, Xia, Eckel, Sandrah P, Berhane, Kiros, Gauderman, W James, Granell, Raquel, Evans, David M, St Pourcain, Beate, McArdle, Wendy, Kemp, John P, Smith, George Davey, Tiesler, Carla MT, Flexeder, Claudia, Simpson, Angela, Murray, Clare S, Fuchs, Oliver, Postma, Dirkje S, Bønnelykke, Klaus, Torrent, Maties, Andersson, Martin, Sleiman, Patrick, Hakonarson, Hakon, Cookson, William O, Moffatt, Miriam F, Paternoster, Lavinia, Melén, Erik, Sunyer, Jordi, Bisgaard, Hans, Koppelman, Gerard H, Ege, Markus, Custovic, Adnan, Heinrich, Joachim, Gilliland, Frank D, Henderson, Alexander J, Jaddoe, Vincent WV, de Jongste, Johan C
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334587/
https://ncbi.nlm.nih.gov/pubmed/24315451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.08.053
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