Fractional exhaled nitric oxide in childhood is associated with 17q11.2-q12 and 17q12-q21 variants

BACKGROUND: The fractional concentration of nitric oxide in exhaled air (FeNO) is a biomarker of eosinophilic airway inflammation and associated with childhood asthma. Identification of common genetic variants associated with childhood FeNO may help to define biological mechanisms related to specifi...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: van der Valk, Ralf JP, Duijts, Liesbeth, Timpson, Nicolas J, Salam, Muhammad T, Standl, Marie, Curtin, John A, Genuneit, Jon, Kerhof, Marjan, Kreiner-Møller, Eskil, Cáceres, Alejandro, Gref, Anna, Liang, Liming L, Taal, H Rob, Bouzigon, Emmanuelle, Demenais, Florence, Nadif, Rachel, Ober, Carole, Thompson, Emma E, Estrada, Karol, Hofman, Albert, Uitterlinden, André G, van Duijn, Cornélia, Rivadeneira, Fernando, Li, Xia, Eckel, Sandrah P, Berhane, Kiros, Gauderman, W James, Granell, Raquel, Evans, David M, St Pourcain, Beate, McArdle, Wendy, Kemp, John P, Smith, George Davey, Tiesler, Carla MT, Flexeder, Claudia, Simpson, Angela, Murray, Clare S, Fuchs, Oliver, Postma, Dirkje S, Bønnelykke, Klaus, Torrent, Maties, Andersson, Martin, Sleiman, Patrick, Hakonarson, Hakon, Cookson, William O, Moffatt, Miriam F, Paternoster, Lavinia, Melén, Erik, Sunyer, Jordi, Bisgaard, Hans, Koppelman, Gerard H, Ege, Markus, Custovic, Adnan, Heinrich, Joachim, Gilliland, Frank D, Henderson, Alexander J, Jaddoe, Vincent WV, de Jongste, Johan C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334587/
https://ncbi.nlm.nih.gov/pubmed/24315451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.08.053
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