A decade of research on the 17q12-21 asthma locus: Piecing together the puzzle

Chromosome 17q12–21 remains the most highly replicated and significant asthma locus. Genotypes in the core region defined by the first genome-wide association study correlate with expression of 2 genes, ORM1-like 3 (ORMDL3) and gasdermin B (GSDMB), making these prime candidate asthma genes, although...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Stein, Michelle M., Thompson, Emma E., Schoettler, Nathan, Helling, Britney A., Magnaye, Kevin M., Stanhope, Catherine, Igartua, Catherine, Morin, Andreanne, Washington, Charles, Nicolae, Dan, Bønnelykke, Klaus, Ober, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172038/
https://ncbi.nlm.nih.gov/pubmed/29307657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.12.974
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