Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Pancreatic cancer is one of the most lethal malignancies due to its late diagnosis and limited response to treatment. Tractable methods to identify and interrogate pathways involved in pancreatic tumorigenesis are urgently needed. We established organoid models from normal and neoplastic murine and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell
Prif Awduron: Boj, Sylvia F., Hwang, Chang-Il, Baker, Lindsey A., Chio, Iok In Christine, Engle, Dannielle D., Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S., Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H., van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D., Wilson, John P., Feigin, Michael E., Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M., Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N., Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H.M., Molenaar, I. Quintus, Borel Rinkes, Inne H., Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J., Iacobuzio-Donahue, Christine, Leach, Steven D., Pappin, Darryl J., Hammell, Molly, Klimstra, David S., Basturk, Olca, Hruban, Ralph H., Offerhaus, George Johan, Vries, Robert G.J., Clevers, Hans, Tuveson, David A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334572/
https://ncbi.nlm.nih.gov/pubmed/25557080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.12.021
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