Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Pancreatic cancer is one of the most lethal malignancies due to its late diagnosis and limited response to treatment. Tractable methods to identify and interrogate pathways involved in pancreatic tumorigenesis are urgently needed. We established organoid models from normal and neoplastic murine and...

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Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Boj, Sylvia F., Hwang, Chang-Il, Baker, Lindsey A., Chio, Iok In Christine, Engle, Dannielle D., Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S., Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H., van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D., Wilson, John P., Feigin, Michael E., Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M., Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N., Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H.M., Molenaar, I. Quintus, Borel Rinkes, Inne H., Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J., Iacobuzio-Donahue, Christine, Leach, Steven D., Pappin, Darryl J., Hammell, Molly, Klimstra, David S., Basturk, Olca, Hruban, Ralph H., Offerhaus, George Johan, Vries, Robert G.J., Clevers, Hans, Tuveson, David A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334572/
https://ncbi.nlm.nih.gov/pubmed/25557080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.12.021
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