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The RAS and YAP1 dance, who is leading?

The Hippo-signaling effector YAP1 was recently found to compensate for oncogenic RAS in certain neoplasms, suggesting so far unanticipated molecular interplays between these major signaling routes. A new study in this issue of The EMBO Journal details KRAS-dependent control of YAP1 stability as well...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Corbo, Vincenzo, Ponz-Sarvise, Mariano, Tuveson, David A
Format: Artigo
Langue:Inglês
Publié: BlackWell Publishing Ltd 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4283400/
https://ncbi.nlm.nih.gov/pubmed/25257311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490014
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