Molecular Umbrella Conjugate for the Ocular Delivery of siRNA

[Image: see text] The synthesis, computer modeling, and biological activity of an octawalled molecular umbrella short interfacing RNA (siRNA) conjugate is described. This molecular umbrella–siRNA conjugate exhibited mRNA knockdown activity in vitro in the absence of a transfection reagent. Evaluatio...

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書誌詳細
出版年:Bioconjug Chem
主要な著者: Janout, Vaclav, Cline, Lauren L., Feuston, Bradley P., Klein, Lee, O’Brien, Ann, Tucker, Tom, Yuan, Yu, O’Neill-Davis, Lynn A., Peiffer, Robert L., Nerurkar, Sandhya S., Jadhav, Vasant, Tellers, David M., Regen, Steven L.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334295/
https://ncbi.nlm.nih.gov/pubmed/24433067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400506m
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