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A Molecular Umbrella Approach to the Intracellular Delivery of siRNA

A series of diwalled and tetrawalled molecular umbrellas have been synthesized using cholic acid, spermidine, and lysine as starting material. Coupling of these molecular umbrellas to an octaarginine peptide afforded agents that were capable of promoting the transport of small interfering RNA (siRNA...

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書目詳細資料
Main Authors: Cline, Lauren L., Janout, Vaclav, Fisher, Michael, Juliano, Rudolph L., Regen, Steven L.
格式: Artigo
語言:Inglês
出版: 2011
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218225/
https://ncbi.nlm.nih.gov/pubmed/21985221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200347x
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