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Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles

The siRNA transfection efficiency of nanoparticles (NPs), composed of a superparamagnetic iron oxide core modified with polycationic polymers (poly(hexamethylene biguanide) or branched polyethyleneimine), were studied in CHO-K1 and HeLa cell lines. Both NPs demonstrated to be good siRNA transfection...

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Bibliographic Details
Main Authors: Castillo, Betzaida, Bromberg, Lev, López, Xaira, Badillo, Valerie, González Feliciano, Jose A., González, Carlos I., Hatton, T. Alan, Barletta, Gabriel
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437298/
https://ncbi.nlm.nih.gov/pubmed/22970377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/218940
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