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Muscle dystrophy-causing ΔK32 lamin A/C mutant does not impair functions of nucleoplasmic LAP2α - lamin A/C complexes in mice

A-type lamins are components of the nuclear lamina, a filamentous network of the nuclear envelope in metazoans that supports nuclear architecture. In addition, lamin A/C can also be found in the nuclear interior. This nucleoplasmic lamin pool is soluble in physiological buffer, depends on the presen...

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Publicado en:J Cell Sci
Autores principales: Pilat, Ursula, Dechat, Thomas, Bertrand, Anne T, Woisetschläger, Nikola, Gotic, Ivana, Spilka, Rita, Biadasiewicz, Katarzyna, Bonne, Gisèle, Foisner, Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333763/
https://ncbi.nlm.nih.gov/pubmed/23444379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.115246
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