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Nucleoplasmic lamins define growth-regulating functions of lamina-associated polypeptide 2α in progeria cells
A-type lamins are components of the peripheral nuclear lamina but also localize in the nuclear interior in a complex with lamina-associated polypeptide (LAP) 2α. Loss of LAP2α and nucleoplasmic lamins in wild-type cells increases cell proliferation, but in cells expressing progerin (a mutant lamin A...
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| Vydáno v: | J Cell Sci |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Company of Biologists Ltd
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826045/ https://ncbi.nlm.nih.gov/pubmed/29361532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.208462 |
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