Nucleoplasmic LAP2α–lamin A complexes are required to maintain a proliferative state in human fibroblasts

In human diploid fibroblasts (HDFs), expression of lamina-associated polypeptide 2 α (LAP2α) upon entry and exit from G(0) is tightly correlated with phosphorylation and subnuclear localization of retinoblastoma protein (Rb). Phosphoisoforms of Rb and LAP2α are down-regulated in G(0). Although RbS78...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Pekovic, Vanja, Harborth, Jens, Broers, Jos L.V., Ramaekers, Frans C.S., van Engelen, Baziel, Lammens, Martin, von Zglinicki, Thomas, Foisner, Roland, Hutchison, Chris, Markiewicz, Ewa
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2007
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063936/
https://ncbi.nlm.nih.gov/pubmed/17227891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606139
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk