LAP2α loss impairs heart function and stress response in mice

RATIONALE: Lamina-Associated Polypeptide 2α (LAP2α) is a mammalian chromatin-binding protein that interacts with a fraction of A-type lamins in the nuclear interior. As mutations in lamins and LAP2α lead to cardiac disorders in humans, we hypothesized that these factors may play important roles in h...

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Autores principales: Gotic, Ivana, Leschnik, Michael, Kolm, Ursula, Markovic, Mato, Haubner, Bernhard J., Biadasiewicz, Katarzyna, Metzler, Bernhard, Stewart, Colin L., Foisner, Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818815/
https://ncbi.nlm.nih.gov/pubmed/19926876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.205724
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