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LAP2α loss impairs heart function and stress response in mice
RATIONALE: Lamina-Associated Polypeptide 2α (LAP2α) is a mammalian chromatin-binding protein that interacts with a fraction of A-type lamins in the nuclear interior. As mutations in lamins and LAP2α lead to cardiac disorders in humans, we hypothesized that these factors may play important roles in h...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818815/ https://ncbi.nlm.nih.gov/pubmed/19926876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.205724 |
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