Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α

Mutations in lamin A/C result in a range of tissue-specific disorders collectively called laminopathies. Of these, Emery–Dreifuss and Limb-Girdle muscular dystrophy 1B mainly affect striated muscle. A useful model for understanding both laminopathies and lamin A/C function is the Lmna(−/−) mouse. We...

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Main Authors: Cohen, Tatiana V., Gnocchi, Viola F., Cohen, Jonathan E., Phadke, Aditi, Liu, Henry, Ellis, Juliet A., Foisner, Roland, Stewart, Colin L., Zammit, Peter S., Partridge, Terence A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888145/
https://ncbi.nlm.nih.gov/pubmed/23535822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt135
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