Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins

AIMS: Given the clinical impact of LMNA cardiomyopathies, understanding lamin function will fulfill a clinical need and will lead to advancement in the treatment of heart failure. A multidisciplinary approach combining cell biology, atomic force microscopy (AFM), and molecular modeling was used to a...

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Bibliographic Details
Published in:Cardiovasc Res
Main Authors: Laurini, Erik, Martinelli, Valentina, Lanzicher, Thomas, Puzzi, Luca, Borin, Daniele, Chen, Suet Nee, Long, Carlin S, Lee, Patrice, Mestroni, Luisa, Taylor, Matthew R G, Sbaizero, Orfeo, Pricl, Sabrina
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909658/
https://ncbi.nlm.nih.gov/pubmed/29432544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy040
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