The Cardiomyopathy Lamin A/C D192G Mutation Disrupts Whole-Cell Biomechanics in Cardiomyocytes as Measured by Atomic Force Microscopy Loading-Unloading Curve Analysis

Atomic force microscopy (AFM) cell loading/unloading curves were used to provide comprehensive insights into biomechanical behavior of cardiomyocytes carrying the lamin A/C (LMNA) D192G mutation known to cause defective nuclear wall, myopathy and severe cardiomyopathy. Our results suggested that the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lanzicher, Thomas, Martinelli, Valentina, Puzzi, Luca, Del Favero, Giorgia, Codan, Barbara, Long, Carlin S., Mestroni, Luisa, Taylor, Matthew R. G., Sbaizero, Orfeo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555041/
https://ncbi.nlm.nih.gov/pubmed/26323789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13388
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