Biomechanical defects and rescue of cardiomyocytes expressing pathologic nuclear lamins

AIMS: Given the clinical impact of LMNA cardiomyopathies, understanding lamin function will fulfill a clinical need and will lead to advancement in the treatment of heart failure. A multidisciplinary approach combining cell biology, atomic force microscopy (AFM), and molecular modeling was used to a...

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Vydáno v:Cardiovasc Res
Hlavní autoři: Laurini, Erik, Martinelli, Valentina, Lanzicher, Thomas, Puzzi, Luca, Borin, Daniele, Chen, Suet Nee, Long, Carlin S, Lee, Patrice, Mestroni, Luisa, Taylor, Matthew R G, Sbaizero, Orfeo, Pricl, Sabrina
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5909658/
https://ncbi.nlm.nih.gov/pubmed/29432544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy040
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