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Protein Conformational Landscapes and Catalysis. Influence of Active Site Conformations in the Reaction Catalyzed by L-Lactate Dehydrogenase

In the last decade L-Lactate Dehydrogenase (LDH) has become an extremely useful marker in both clinical diagnosis and in monitoring the course of many human diseases. It has been assumed from the 80s that the full catalytic process of LDH starts with the binding of the cofactor and the substrate fol...

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Publicat a:ACS Catal
Autors principals: Świderek, Katarzyna, Tuñón, Iñaki, Martí, Sergio, Moliner, Vicent
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333743/
https://ncbi.nlm.nih.gov/pubmed/25705562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cs501704f
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