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Peptide Bond Formation Mechanism Catalyzed by Ribosome

In this paper we present a study of the peptide bond formation reaction catalyzed by ribosome. Different mechanistic proposals have been explored by means of Free Energy Perturbation methods within hybrid QM/MM potentials, where the chemical system has been described by the M06-2X functional and the...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Świderek, Katarzyna, Marti, Sergio, Tuñón, Iñaki, Moliner, Vicent, Bertran, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582011/
https://ncbi.nlm.nih.gov/pubmed/26325003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b05916
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