Structured Observations Reveal Slow HIV-1 CTL Escape

The existence of viral variants that escape from the selection pressures imposed by cytotoxic T-lymphocytes (CTLs) in HIV-1 infection is well documented, but it is unclear when they arise, with reported measures of the time to escape in individuals ranging from days to years. A study of participants...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Roberts, Hannah E., Hurst, Jacob, Robinson, Nicola, Brown, Helen, Flanagan, Peter, Vass, Laura, Fidler, Sarah, Weber, Jonathan, Babiker, Abdel, Phillips, Rodney E., McLean, Angela R., Frater, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333731/
https://ncbi.nlm.nih.gov/pubmed/25642847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004914
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