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Direct β-Alkylation of Aldehydes via Photoredox Organocatalysis

[Image: see text] Direct β-alkylation of saturated aldehydes has been accomplished by synergistically combining photoredox catalysis and organocatalysis. Photon-induced enamine oxidation provides an activated β-enaminyl radical intermediate, which readily combines with a wide range of Michael accept...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Terrett, Jack A., Clift, Michael D., MacMillan, David W. C.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333594/
https://ncbi.nlm.nih.gov/pubmed/24754456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja502639e
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