BRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma patients

BACKGROUND: This study aimed to determine whether the BRCA1 haplotype was associated with trabectedin efficacy in soft-tissue sarcoma (STS) patients. METHODS: We analysed BRCA1 single-nucleotide polymorphisms (SNPs) in tumour specimens from 135 advanced STS patients enrolled in published phase 2 tri...

Fuld beskrivelse

Na minha lista:

Bibliografiske detaljer
Udgivet i:	Br J Cancer
Main Authors:	Laroche-Clary, A, Chaire, V, Le Morvan, V, Neuville, A, Bertucci, F, Salas, S, Sanfilippo, R, Pourquier, P, Italiano, A
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2015
Fag:	Translational Therapeutics
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4333490/ https://ncbi.nlm.nih.gov/pubmed/25602962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.624
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!

BRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma patients

Lignende værker