BRCA1 haplotype and clinical benefit of trabectedin in soft-tissue sarcoma patients

BACKGROUND: This study aimed to determine whether the BRCA1 haplotype was associated with trabectedin efficacy in soft-tissue sarcoma (STS) patients. METHODS: We analysed BRCA1 single-nucleotide polymorphisms (SNPs) in tumour specimens from 135 advanced STS patients enrolled in published phase 2 tri...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Laroche-Clary, A, Chaire, V, Le Morvan, V, Neuville, A, Bertucci, F, Salas, S, Sanfilippo, R, Pourquier, P, Italiano, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4333490/
https://ncbi.nlm.nih.gov/pubmed/25602962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.624
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados