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PRIMA-1(MET) induces death in soft-tissue sarcomas cell independent of p53
BACKGROUND: The aim of this study was to explore the efficacy and define mechanisms of action of PRIMA-1(MET) as a TP53 targeted therapy in soft-tissue sarcoma (STS) cells. METHODS: We investigated effects of PRIMA-1(MET) on apoptosis, cell cycle, and induction of oxidative stress and autophagy in a...
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Publicado no: | BMC Cancer |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604610/ https://ncbi.nlm.nih.gov/pubmed/26463477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1667-1 |
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