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Structure of Sickled Erythrocytes and of Sickle-Cell Hemoglobin Fibers

Deoxyhemoglobin from patients homozygous for sickle-cell anemia (deoxyhb S) aggregates into long straight fibers. These may extend through most of the length of the sickled cell, forming either square or hexagonally packed bundles with lattice constants of 170-180 Å. Each fiber is a tube made up of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Finch, J. T., Perutz, M. F., Bertles, J. F., Döbler, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4123689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.3.718
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