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Structure of Sickled Erythrocytes and of Sickle-Cell Hemoglobin Fibers

Deoxyhemoglobin from patients homozygous for sickle-cell anemia (deoxyhb S) aggregates into long straight fibers. These may extend through most of the length of the sickled cell, forming either square or hexagonally packed bundles with lattice constants of 170-180 Å. Each fiber is a tube made up of...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Finch, J. T., Perutz, M. F., Bertles, J. F., Döbler, Johanna
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1973
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4123689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.3.718
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