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Structure of Sickled Erythrocytes and of Sickle-Cell Hemoglobin Fibers

Deoxyhemoglobin from patients homozygous for sickle-cell anemia (deoxyhb S) aggregates into long straight fibers. These may extend through most of the length of the sickled cell, forming either square or hexagonally packed bundles with lattice constants of 170-180 Å. Each fiber is a tube made up of...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Finch, J. T., Perutz, M. F., Bertles, J. F., Döbler, Johanna
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1973
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC433343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4123689/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.70.3.718
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